Laboratory 7
17 February 2011
Kidney disease
Pre-lab lecture
ESRD-pathology
-urea and creatinine
-blood plasma urea and creatinine versus urinary urea and creatinine
-types 1 and 2 diabetes
-atherosclerosis
-hypertension
-all above contribute to stroke and therefore factors contributing to stroke also contribute to ESRD risk
-blood plasma fasting glucose
-blood plasma lipids and lipoproteins
-blood pressure
-body fat
-platelet reactivity
-nutrient intake
Results
With ESRD Without ESRD
-blood plasma urea 200 26
-blood plasma creatinine 6 1
-urinary urea (urea nitrogen) 0 13
-urinary creatinine (mg/kg/24 hour) 0 17
-blood plasma fasting glucose 180 85
-blood plasma fasting
triglycerides 116 85
cholesterol 190 140
HDL-c 42 50
LDL-c 129 90
-Blood pressure 141/82 126/80
-platelet reactivity (bleeding time) 30 6
-BMI (not significantly different) 24.7 24.5
-nutrient intake
protein (g/kg/d) less than 0.8 0.8
potassium 2000 mg/d yield by
Canada’s food guide
phosphorous 1 serving of yield by
high phosphorous Canada’s food guide
foods per day
calcium reduce milk product yield by
servings to tolerated Canada’s food guide
levels
sodium reduce food yield by
servings to tolerated Canada’s food guide
All values are fasting and in mg/dl unless otherwise specified.
Unless otherwise specified all values are significantly different
on the same measure
Introduction
Hypothesis
Objective
Methods
Results
Discussion- compare suggested dietary intakes for ESRD with dietary intake measures for preventing ESRD
Conclusions