Laboratory 4- 20 Jan 2011
Atherosclerosis
Pre-lab lecture-atherosclerosis pathology
atherosclerotic disease atherosclerotic disease
-plasma triglycerides 450 100
-plasma cholesterol 300 150
-plasma HDL-cholesterol 20 50
-plasma LDL-cholesterol 190 80
-plasma LDL size(angstroms) 250 270
-plasma Lp(a) 50 1
-plasma VLDL-cholesterol 90 20
-plasma chylomicrons-triglyceride 80 54
(4 hours post-prandial)
-blood pressure(mm Hg) 180/100 110/80
-height
-weight
-BMI(kg/m2) 35 22
-waist circumference(cm) 110 60
-platelet reactivity bleeding time 2.5 6.0
(minutes)
Introduction
Why are waist circumference, blood lipid and lipoprotein concentrations, blood pressure and platelet reactivity of significance in human atherosclerosis?
Hypothesis
What would one hypothesise to be the differences in waist circumference, blood lipid and lipoprotein concentrations, blood pressure and platelet reactivity between the 2 groups and why?
Objective
Methods
How does one measure waist circumference, blood lipid and lipoprotein concentrations, blood pressure and platelet reactivity?
Results
What are the differences in waist circumference, blood lipid and lipoprotein concentrations, blood pressure and platelet reactivity between the 2 groups and indicate the correlation between waist circumference and each of blood lipid and lipoprotein concentrations, blood pressure and platelet reactivity within each of the 2 groups?
Discussion
Explain the results.
Conclusions
What would one conclude about differences in waist circumference, blood lipid and lipoprotein concentrations, blood pressure and platelet reactivity between the 2 groups?